Boric acid ph is an important component of many baby powders, antiseptics, diaper rash ointments, eye washes and gargles. It is also used as a fungicide and insecticide.
The metabolism of inorganic borates by biological systems is not feasible due to the excessive energy (523 kJ/mol) required to break the boron-oxygen bond. This property is supported by the fact that more than 90% of administered doses of inorganic borates are excreted as boric acid in the urine.
Toxicology of boric acid ph:
The toxicological effects of boric acid are similar to those of other inorganic boron compounds and include gastrointestinal tract irritation, eye toxicity, skin irritability, urological complications and reproductive toxicity. These effects are dose dependent and appear to be mediated through an affinity for cis-hydroxyl groups, but it is unknown whether or not this binding mechanism is the only underlying effect.
Exploring the pH Balancing Properties of Boric Acid and Its Benefits for Vaginal Health
Developmental toxicity:
The developmental toxicity of boric acid is characterized by increased mortality in the postimplantation period (pnd) and reduced fetal body weight at low and high doses, although it does not appear to result in an increase in ventricular enlargement. The NOAEL for maternal toxicity was 0.1% of boric acid intake and the LOAEL was 0.2%.
Embryo/fetal toxicity:
The incidence of fetal malformations was significantly increased at greater than or equal to 0.2% of boric acid intake (2, 3, 8, 50 and 73% malformed fetuses/litter). This was primarily associated with enlarged lateral ventricles of the brain, as well as agenesis or shortening of rib XIII.